During the procedure, patients experience reduction in pain and anxiety due to the analgesic and anxiolytic properties of nitrous oxide. After the procedure, the effects on the patient wear off within minutes.
Mechanism of action: nitrous oxide is predominately a NMDA-receptor antagonist, with little or no effect at GABAA receptors. It is also known to have stimulatory effects on dopamine, α1- and α2-adrenergic and opioid receptors.
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