Indications:
The needles also breakdown the old, hardened scar strands and allow it to revascularize. Neovascularization and neocollagenesis is initiated by migration and proliferation of fibroblasts and laying down of intercellular matrix. A fibronectin matrix forms after 5 days of injury that determines the deposition of collagen resulting in skin tightening persisting for 5–7 years in the form of collagen III. The depth of neocollagenesis has been found to be 5–600 µm with a 1.5 mm length needle. Histological examination of the skin treated with 4 microneedling sessions 1 month apart shows up to 400% increase in collagen and elastin deposition at 6 months postoperatively, with a thickened stratum spinosum and normal rete ridges at 1 year postoperatively. Collagen fiber bundles appear to have a normal lattice pattern rather than parallel bundles as in scar tissue.
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